Eddouks, M. and Bidi, A. and El Bouhali, B. and Hajji, L. and Zeggwagh, N.A. (2014) Antidiabetic plants improving insulin sensitivity. Journal of Pharmacy and Pharmacology, 66 (9). pp. 1197-1214.

Full text not available from this repository.
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background Globally, the prevalence of diabetes mellitus is increasing at an alarming rate. This chronic pathology gravely troubled the human health and quality of life. Both insulin deficiency and insulin resistance are involved in the pathophysiology of diabetes mellitus. Moreover, insulin resistance is being diagnosed nowadays in a growing population of diabetic and obese patients, especially in industrialized societies. There are lots of conventional agents available to control and to treat diabetes, but total recovery from this disorder has not been reported up to this date. Plants provided a potential source of hypoglycemic drugs and are widely used in several traditional systems of medicine to prevent diabetes. A few reviews with less attention paid to mechanisms of action have been published on antidiabetic plants. Objectives The present review focuses on the various plants that have been reported to be effective in improving insulin sensitivity associated with diabetes. Key findings In this work, an updated systematic review of the published literature has been conducted to review the antidiabetic plants improving insulin sensitivity and 111 medicinal plants have been reported to have a beneficial effect on insulin sensitivity using several in-vitro and in-vivo animal models of diabetes. Conclusion The different metabolic and cellular effects of the antidiabetic plants improving insulin sensitivity are reported indicating the important role of medicinal plants as potential alternative or complementary use in controlling insulin resistance associated with diabetes mellitus. © 2014 Royal Pharmaceutical Society.

Item Type: Article
Uncontrolled Keywords: aloe emodin; Aloe vera extract; aloin; amorfrutin; angeloylgomisin h; aromadendrin; astragaloside II; bellidifolin; borapetoside C; chlorogenic acid; decursin; diavite; ginsenoside; glucoside; gomisin A; isoastragaloside i; karanjin; lignan; mangiferin; methylswertianin; naringenin; natural product; polysaccharide; procyanidin derivative; quercetin; quercetin 3 o glycoside; schizandrin; secoaggregatalactone A; unclassified drug; unindexed drug; vescalagin; antidiabetic agent; insulin; plant medicinal product, Abelmoschus moschatus; Abutilon indicum; Aloe vera; Alpinia pricei; amorpha fruticosa; Anemarrhena asphodeloides; antidiabetic activity; artemisia herba alba; Artemisia sphaerocephala; Astragalus membranaceus; Atractylis japonica; Aucklandia Lappa; Bidens pilosa; black cumin; Brassica juncea; bumelia sartorum; Calotropis gigantea; Canna indica; Cayratia trifolia; cecropia obtusifolia; Centaurium erythraea; Cinnamomum cassia; Cistus salviifolius; Citrus junos; Cleome droserifolia; coriander; Cornus kousa; Cornus officinalis; cranberry; Crocus sativus; cryptolepis sanguinolenta; Curcuma comosa; Cyclea peltata; diabetes mellitus; disease association; disease model; drug mechanism; Dryopteris fragrans; Echinacea purpurea; Elaeis guineensis; Enicostema littorale; euryale ferox; fenugreek; Ficus deltoidea; Ganoderma lucidum; garlic; Gastrodia elata; germander; ginger; ginseng; Gleditsia sinensis; Glycyrrhiza foetida; guava; Guazuma ulmifolia; Hedysarum polybotrys; Helicteres isora; human; Ilex hunanensis; impaired glucose tolerance; in vitro study; in vivo study; insulin resistance; insulin sensitivity; Jerusalem artichoke; Justicia adhatoda; Justicia spicigera; Kigelia pinnata; kino; Krameria lappacea; Lagerstroemia speciosa; Larix laricina; Lindera aggregata; lingonberry; Liriope spicata; Litsea coreana; Lyophyllum decastes; Magnolia dealbata; malva parviflora; mango; medicinal plant; Momordica charantia; non insulin dependent diabetes mellitus; nonhuman; Nyctanthes arbortristis; olive tree; Ophiopogon japonicus; Opuntia dillenii; Passiflora nitida; Phellodendri cortex; pineapple; Pongamia pinnata; Populus balsamifera; Prosopis glandulosa; Prunus mume; Psacalium peltatum; Pueraria thomsonii; Rehmannia glutinosa; review; Rhodiola crenulata; Rhus coriaria; Sambucus nigra; Schisandra chinensis; Scoparia dulcis; Smallanthus sonchifolius; Sorbus decora; Spergularia purpurea; Stevia; streptozotocin-induced diabetes mellitus; Suaeda fruticosa; Sutherlandia frutescens; Swertia punicea; Symplocos cochinchinensis; systematic review; Syzygium cumini; Syzygium jambo; Syzygium samarangense; Tecoma stans; Tetrastigma obtectum; Teucrium cubense; Tinospora cordifolia; Tinospora crispa; Tithonia diversifolia; Vaccinium angustifolium; Vaccinium myrtillus; Vatairea macrocarpa; Xanthium strumarium; Ziziphus spina christi; animal; Diabetes Mellitus, Type 2; insulin resistance; metabolism; phytotherapy, Animals; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Phytotherapy; Plant Preparations; Plants, Medicinal
Subjects: Pharmacology, Toxicology and Pharmaceutics
Divisions: SCIENTIFIC PRODUCTION > Pharmacology, Toxicology and Pharmaceutics
Depositing User: Administrateur Eprints Administrateur Eprints
Last Modified: 31 Jan 2020 15:49
URI: http://eprints.umi.ac.ma/id/eprint/4397

Actions (login required)

View Item View Item