Bouharb, H. and Badaoui, K.E. and Zair, T. and Shisseh, H. and Chakir, S. and Alaoui, T. (2014) Antibacterial evaluation and phytochemical screening of Eucalyptus gomphocephala DC against Pseudomonas aeruginosa. Asian Journal of Pharmaceutical and Clinical Research, 7 (5). pp. 264-267.

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Results: The present study reveals that the essential oil does not show any activity against all strains. Extracts showed varying degrees of inhibition on the tested microorganisms. The petroleum ether and ethanol had a lower activity against strains. However, aqueous and hexane leaf extracts, of E. gomphocephala presented the highest anti P. aeruginosa activity against all strains tested. The MIC and minimum bactericidal concentration of the aqueous and hexane extracts ranged between 6.25 and 50 mg/ml. Qualitative analysis of E. gomphocephala revealed the presence of biological active compounds such as tannins, flavonoids, saponins and steroids/triterpenes. Conclusion: To conclude, extracts of E. gomphocephala leaf may be pursued as an antibacterial agent for the treatment of infections caused by P. aeruginosa. Objective: The aim was to evaluate the in vitro antibacterial activities of essential oil and extracts from Eucalyptus gomphocephala leaf on the growth of six strains of Pseudomonas aeruginosa. Methods: Aqueous, ethanol, hexane, petroleum ether extracts and essential oil of E. gomphocephala leaf were investigated on six strains of P. aeruginosa. The antibacterial activity was determined by agar-well diffusion method and expressed as the average diameter of the zone of inhibition of bacterial growth around the wells. The minimum inhibitory concentration (MIC) of active extracts was determined by microdilution assay. The preliminary phytochemical screening of the leaf was conducted using various standard methods. © 2014, Asian Journal of Pharmaceutical and Clinical Research. All rights reserved.

Item Type: Article
Uncontrolled Keywords: alcohol; antiinfective agent; Eucalyptus gomphocephala extract; Eucalyptus gomphocephala oil; eucalyptus oil; flavanoid; gentamicin; hexane; petroleum ether; phytosterol; plant extract; saponin; tannin derivative; triterpene; unclassified drug, agar diffusion; antibacterial activity; aqueous solution; Article; bacterial growth; bacterial strain; broth dilution; concentration response; controlled study; drug screening; Eucalyptus; Eucalyptus gomphocephala; growth inhibition; minimum bactericidal concentration; minimum inhibitory concentration; nonhuman; phytochemistry; plant leaf; Pseudomonas aeruginosa; qualitative analysis; solvent effect
Subjects: Medicine
Depositing User: Administrateur Eprints Administrateur Eprints
Last Modified: 31 Jan 2020 15:49

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