Rougeron, A. and Giraud, S. and Alastruey-Izquierdo, A. and Cano-Lira, J. and Rainer, J. and Mouhajir, A. and Le Gal, S. and Nevez, G. and Meyer, W. and Bouchara, J.P. (2018) Ecology of Scedosporium Species: Present Knowledge and Future Research. Mycopathologia, 183 (1). pp. 185-200.

Full text not available from this repository.
Official URL:


The genus Scedosporium, which comprises at least five clinically relevant species, i.e. Scedosporium apiospermum, Scedosporium boydii, Scedosporium aurantiacum, Scedosporium dehoogii and Scedosporium minutisporum, ranks the second among the filamentous fungi colonizing the airways of patients with cystic fibrosis (CF). This colonization of the airways is thought to contribute to the inflammatory reaction leading to a progressive deterioration of the lung function. Additionally, these colonizing fungi may lead to severe disseminated infections in case of lung transplantation. Therefore, considering the low susceptibility of Scedosporium species to all current antifungal drugs, preventive measures should be defined to reduce the risk of exposure to these fungi for non-colonized CF patients. With this in mind, several studies have been conducted to elucidate the ecology of these fungi and to define possible sources of patient contamination. This review will summarize the major outcomes of those studies, including: the clear demonstration that ecological niches of Scedosporium species are strongly impacted by human activities, and the ability of Scedosporium species to degrade aliphatic and aromatic pollutants which supports the high occurrence of these species in contaminated soils and polluted waters and makes them promising candidates for bioremediation purposes. Finally, prospects for future research in this field are proposed. © 2017, Springer Science+Business Media B.V.

Item Type: Article
Uncontrolled Keywords: classification; complication; cystic fibrosis; environmental exposure; growth, development and aging; human; isolation and purification; lung mycosis; microbiology; Scedosporium, Cystic Fibrosis; Environmental Exposure; Humans; Lung Diseases, Fungal; Scedosporium
Subjects: Agricultural and Biological Sciences
Divisions: SCIENTIFIC PRODUCTION > Agricultural and Biological Sciences
Depositing User: Administrateur Eprints Administrateur Eprints
Last Modified: 31 Jan 2020 15:44

Actions (login required)

View Item View Item